Compound Identity
What Is BPC-157?
BPC-157 — Body Protection Compound 157 — is a synthetic pentadecapeptide comprised of 15 amino acids. The sequence was isolated from human gastric juice, where a similar partial sequence occurs naturally. Foundational research on this compound was conducted by Dr. Predrag Sikiric and his team at the University of Zagreb, with their preclinical studies forming the basis of a now-expansive body of published literature.
Compound Class
Pentadecapeptide (15 amino acids)
Body Protection Compound
Body Protection Compound
Origin Source
Sequence isolated from human gastric juice; synthetic production for research
Molecular Weight
1,419.53 g/mol
CAS: 137525-51-0
CAS: 137525-51-0
Foundational Research
Dr. Predrag Sikiric, University of Zagreb
Research ongoing since the 1990s
Research ongoing since the 1990s
Amino Acid Sequence
Gly — Glu — Pro — Pro — Pro — Gly — Lys — Pro — Ala — Asp — Asp — Ala — Gly — Leu — Val
Research Background
Published Research Areas
With over 200 peer-reviewed publications indexed on PubMed, BPC-157 stands among the most studied synthetic peptides in preclinical science. Published research has examined the compound across multiple biological systems and research contexts — all framed as preclinical investigation for research purposes.
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Gastrointestinal Mucosa Research
Published research has investigated BPC-157 in the context of gastric mucosal integrity and gastrointestinal epithelial structures. This line of research reflects the compound's gastric origin and the early work of the Sikiric group at Zagreb.
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Angiogenesis Studies
Peer-reviewed studies have examined BPC-157 in relation to angiogenic processes — the formation and remodeling of blood vessel structures. Researchers have studied its interactions with vascular endothelial growth factor (VEGF) pathways in preclinical models.
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Nitric Oxide Pathway Research
Published investigations have examined the relationship between BPC-157 and nitric oxide (NO) signaling pathways. Research has explored its interactions with NO synthase systems in preclinical research contexts.
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Tendon & Ligament Tissue Studies
A substantial portion of the published BPC-157 literature examines connective tissue structures — specifically tendon and ligament models. Research has investigated extracellular matrix and fibroblast-related parameters in preclinical settings.
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Gut-Brain Axis Research
Published research has examined BPC-157 within gut-brain axis frameworks, investigating the compound in studies relevant to neuroenteric signaling. This area represents a growing dimension of the published BPC-157 literature.
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Multi-System Preclinical Models
Beyond any single domain, the depth of BPC-157 research spans multiple organ systems in preclinical models. The breadth of published investigation across these areas makes it a reference compound for peptide research programs.
200+ papers indexed on PubMed. Search the full BPC-157 publication index directly via the National Library of Medicine. All research framing on this page reflects the published preclinical literature.
Search PubMed →
Sequence Labs Supply
BPC-157 — Available Sizes & Pricing
All BPC-157 vials are supplied as lyophilized powder, sealed under inert atmosphere, verified by HPLC and mass spectrometry at Krause Analytical (PA). COA available for every batch in the COA Library.
BPC-157
5mg Vial
$38.99
Lyophilized powder · ≥99% purity
HPLC + MS verified · COA included
HPLC + MS verified · COA included
Best Value
BPC-157
10mg Vial
$60.99
Lyophilized powder · ≥99% purity
HPLC + MS verified · COA included
HPLC + MS verified · COA included
BPC-157 + TB-500 Blend
5mg ea (10mg total)
$70.99
5mg BPC-157 + 5mg TB-500
Single vial blend · COA included
Single vial blend · COA included
BPC-157 + TB-500 Blend
10mg ea (20mg total)
Contact for price
10mg BPC-157 + 10mg TB-500
Single vial blend · COA included
Single vial blend · COA included
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Krause Analytical
Independent PA-based laboratory. HPLC and mass spectrometry on every batch.
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Batch COA Transparency
Every batch COA is published in the public COA Library — no request required.
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Sabrina Runbeck, PA-C Catalog
Sequence Labs catalog reviewed by a licensed Physician Assistant-Certified for catalog integrity.
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Finnrick Pulse Monitoring
Market monitoring for supplier-level quality signals and regulatory status changes.
Reconstitution Reference
Preparing BPC-157 Research Preparation
The following is a general reference for handling lyophilized BPC-157 in a research setting. All procedures should be carried out by qualified personnel under appropriate laboratory conditions. For research use only.
Prepare a sterile work environment
Use a laminar flow hood or appropriate biosafety enclosure. Ensure all materials — syringes, solvent vials, and research vials — are sterile and within their indicated use window.
Select appropriate solvent
Bacteriostatic water (0.9% benzyl alcohol) is the standard solvent for BPC-157 lyophilized powder. Sterile water (USP grade) may be used for immediate-use research preparations. The volume of solvent introduced determines the concentration of the resulting research sample.
Introduce solvent to the vial
Draw the required volume of solvent into a sterile syringe. Insert through the rubber stopper and direct the stream slowly down the inner wall of the vial — do not aim directly onto the lyophilized cake. This preserves peptide structure during dissolution.
Gently swirl — do not vortex
Swirl the vial gently in a circular motion until the lyophilized powder is fully dissolved and the solution is clear. Do not vortex or shake vigorously, as mechanical agitation can compromise peptide integrity.
Store reconstituted research preparation
Once solvent has been introduced, store the vial refrigerated at 2–8°C, protected from light. Use within the timeframe appropriate for your research protocol. Lyophilized, unreconstituted vials should be stored at –20°C.
Research use only. These reconstitution notes are provided as a general laboratory reference for qualified researchers. They do not constitute medical advice, dosing guidance, or instructions for human use. All handling of BPC-157 research preparations must comply with applicable institutional, state, and federal regulations.
Common Questions
BPC-157 Research FAQ
What is BPC-157 and where does it come from?
BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide — a chain of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. The sequence was isolated from a partial sequence found in human gastric juice. Extensive foundational research was conducted by Dr. Predrag Sikiric and colleagues at the University of Zagreb, whose work beginning in the 1990s established the preclinical literature base that now comprises 200+ published papers.
How many published studies exist on BPC-157?
Over 200 peer-reviewed papers on BPC-157 are indexed in the PubMed database, making it one of the most extensively studied peptides in preclinical research. This literature spans gastrointestinal research, connective tissue studies, angiogenesis investigations, nitric oxide pathway research, and gut-brain axis studies. The full index is accessible via PubMed's BPC-157 search.
What is the BPC-157 + TB-500 blend and why is it studied together?
The BPC-157 + TB-500 blend combines equal amounts of BPC-157 and Thymosin Beta-4 fragment (TB-500) in a single research vial. Published research has independently examined both peptides in the context of connective tissue and musculoskeletal structures. Researchers investigating complementary biological pathways have studied these two compounds together. Sequence Labs offers the blend at 5mg each (10mg total) and 10mg each (20mg total) per vial, with COA available for each lot.
What purity standard does Sequence Labs use for BPC-157?
All Sequence Labs BPC-157 is independently verified by Krause Analytical, a licensed PA-based third-party laboratory, using both HPLC (high-performance liquid chromatography) and mass spectrometry. Purity is verified at ≥99%. A Certificate of Analysis (COA) is published in the public COA Library for every batch — available without request or account login.
Is BPC-157 available for wholesale B2B?
Yes. Sequence Labs operates a gated wholesale portal with tiered pricing for qualified research institutions, licensed practitioners, and B2B procurement teams. Discount tiers range from approximately 18% to 32% below retail pricing, with no minimum monthly commitment. Apply via the Wholesale page or contact us directly for high-volume inquiries.
How should BPC-157 be stored and reconstituted for research?
Lyophilized BPC-157 powder should be stored at –20°C when not in active research use, protected from light and moisture. To prepare a research sample, introduce bacteriostatic water as solvent by directing the stream slowly down the inner wall of the vial — avoid direct contact with the lyophilized cake. Swirl gently; do not vortex. The reconstituted research preparation should be stored refrigerated at 2–8°C and used within the timeframe appropriate for the research protocol, as determined by the qualified investigator.
Ready to source BPC-157 for your research?
HPLC + MS verified, COA on every batch. Licensed researchers and institutional buyers — browse available sizes or inquire about wholesale volume.