Chemical Identity
What Is Tirzepatide?
Tirzepatide is a synthetic 39-amino acid peptide engineered as a dual incretin receptor agonist — the first of its class to be studied for simultaneous agonism of both the glucagon-like peptide-1 receptor (GLP-1R) and the glucose-dependent insulinotropic polypeptide receptor (GIPR). The molecule incorporates a C20 fatty diacid moiety via a gamma-glutamic acid linker, a structural modification that enables extended plasma half-life through albumin binding. The peptide sequence is derived from the native GIP hormone with additional modifications to achieve balanced GLP-1R and GIPR activity profiles.
- Peptide class: Synthetic acylated peptide; GLP-1/GIP dual receptor agonist (twincretin)
- Structure: 39 amino acids; C20 fatty diacid via gamma-glutamic acid/mini-PEG linker; Aib substitutions at positions 2 and 13 for protease resistance
- Half-life mechanism: Albumin binding via fatty diacid chain; studied for extended duration in receptor binding kinetics research
- Origin: First described in peer-reviewed literature beginning in the mid-2010s as a dual incretin receptor agonist; Sequence Labs supplies a research-grade analog only
- Research grade distinction: Sequence Labs tirzepatide is a laboratory research compound — not a pharmaceutical product, not FDA-approved, and not interchangeable with any marketed medicine
Important: Sequence Labs tirzepatide is a research-grade compound intended for in vitro and preclinical laboratory research by qualified researchers only. It is not an FDA-approved pharmaceutical product and is not a substitute for any marketed medicine. For research use only. Not for human use.
Published Research
Research Background
Peer-reviewed literature on tirzepatide has examined a range of receptor pharmacology and incretin biology questions. Published research consistently frames tirzepatide as a mechanistically distinct compound compared to selective GLP-1 mono-agonists, owing to its engagement of the GIPR alongside GLP-1R. The following areas represent the primary domains investigated in published research.
Explore the full body of published research: Search tirzepatide on PubMed →
Available Vial Sizes & Pricing
Sequence Labs Tirzepatide Supply
Research-grade tirzepatide available in six vial sizes for preclinical, in vitro, and laboratory research applications. All vials lyophilized, batch-tested, and shipped with COA documentation.
| Vial Size | Research Price | Purity | COA |
|---|---|---|---|
| 5mg | $48.99 | ≥98–99% HPLC + MS | ✓ Krause Analytical |
| 10mg | $70.99 | ≥98–99% HPLC + MS | ✓ Krause Analytical |
| 15mg | $97.99 | ≥98–99% HPLC + MS | ✓ Krause Analytical |
| 20mg | $128.99 | ≥98–99% HPLC + MS | ✓ Krause Analytical |
| 30mg | $148.99 | ≥98–99% HPLC + MS | ✓ Krause Analytical |
| 40mg | $234.99 | ≥98–99% HPLC + MS | ✓ Krause Analytical |
- Independent testing: Every batch tested by Krause Analytical (Austin, TX) for identity, purity, and potency via HPLC and mass spectrometry
- COA transparency: Batch-specific certificates of analysis are publicly accessible and cross-verifiable through Finnrick Pulse
- Sabrina Runbeck, PA-C: The Sequence Labs catalog is reviewed by a licensed Physician Assistant-Certified (PA-C) for compound integrity and catalog accuracy
- Lyophilized format: All vials shipped as lyophilized powder for stability during storage and transit; supplied with research data sheet
- Wholesale available: Tiered pricing for laboratories, research institutions, and qualified researchers — inquire via the wholesale portal
Laboratory Handling
Receiving, Storage & COA
Tirzepatide ships as a sealed lyophilized research vial. Receiving, inventory, and any subsequent laboratory preparation follow your institution’s protocols and the batch Certificate of Analysis. Sequence Labs does not publish reconstitution recipes, solvent volumes, or administration how-to.
Research use only. Tirzepatide from Sequence Labs is intended exclusively for preclinical and in vitro research by qualified researchers. Not for human use, self-experimentation, or clinical application.
- 1 Inspect the sealed vial. Confirm the crimp is intact and the lyophilized material is consistent with a sealed research vial before releasing it to inventory.
- 2 Match the batch COA. Verify the lot number against the Krause Analytical Certificate of Analysis (cross-checkable via Finnrick Pulse).
- 3 Store sealed. Keep lyophilized vials protected from light and moisture. Refrigerated storage is the usual default unless the COA or your SOP specifies otherwise.
- 4 Follow institutional SOP. Solvent choice, volumes, and in-use handling are determined by the qualified investigator — not by Sequence Labs.
Common Questions